Mechanism
Synthetic analog of antidiuretic hormone. Concentrates urine and transiently raises von Willebrand factor.
TechnicalSelective V2 receptor agonist; promotes aquaporin-2 trafficking and endothelial release of vWF / factor VIII.
Reported uses by species
| Species | Indication | Tier | Honest evidence note |
|---|---|---|---|
| Dogs | Central diabetes insipidus | Standard-of-care | Maintenance therapy. |
| Dogs | von Willebrand's disease | Standard-of-care | Transiently raises vWF and shortens bleeding time, enabling surgery/bleeding control. |
| Cats | Central DI | Investigational | Used; feline hemostatic effect not yet established. |
Suggested starting protocol
Starting points only — clinical judgment required. Dosing unlocks for verified veterinary accounts.
Professional-use acknowledgment
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Monitoring, contraindications & do-not-use-if
Caution with concurrent fluid loading (risk of hyponatremia). Tachyphylaxis with repeated vWD dosing.
The evidence
- Peptides in Veterinary Medicine — BachemBachem