GnRH agonist

Gonadorelin / GnRH analogs (Deslorelin) Standard-of-care

Controls reproductive cycling — induces ovulation, suppresses estrus, manages fertility.

Mechanism

Controls reproductive cycling — induces ovulation, suppresses estrus, manages fertility.

TechnicalSustained GnRH-R agonism downregulates pituitary FSH/LH after an initial flare; deslorelin implants give 6–12 months of suppression.

Reported uses by species

SpeciesIndicationTierHonest evidence note
DogsReversible suppression of fertilityStandard-of-careDeslorelin implant labeled in many jurisdictions.
Cats / FerretsAdrenal/reproductive diseaseStandard-of-careUsed widely; ferrets — adrenal disease management.
HorsesOvulation inductionStandard-of-careStandard reproductive use.

Suggested starting protocol

Starting points only — clinical judgment required. Dosing unlocks for verified veterinary accounts.

Professional-use acknowledgment

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Monitoring, contraindications & do-not-use-if

Prepubertal use varies by jurisdiction; initial flare may transiently increase fertility.

The evidence

  • Peptides in Veterinary Medicine — Bachem
    Bachem