Mechanism
An active region of thymosin β4 studied for wound, dermal and tendon healing.
TechnicalLKKTETQ (aa 17–23 of Tβ4) drives actin sequestration, cell migration, and angiogenesis. Parent Tβ4 accelerates dermal/tendon healing in animal models.Ac-LKKTETQ
Reported uses by species
| Species | Indication | Tier | Honest evidence note |
|---|---|---|---|
| Horses | Tendon / ligament recovery | Investigational | Largely uncontrolled clinical practice — not RCTs. Detection methods exist in equine plasma/urine. |
| Dogs | Wound and soft-tissue healing | Investigational | Animal-model evidence for parent Tβ4. |
Suggested starting protocol
Starting points only — clinical judgment required. Dosing unlocks for verified veterinary accounts.
Professional-use acknowledgment
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Dosing tables on monographs are for licensed veterinary professionals using independent clinical judgment.
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- • I understand evidence labels reflect the current state of published research.
Monitoring, contraindications & do-not-use-if
BANNED in many racing/competition jurisdictions — verify with governing body before any equine use. Not FDA-approved for veterinary use.
The evidence
- TrimRX evidence review on Tβ4 / TB-500TrimRX
- Equine doping-control J. Chromatogr. A 2012Mad Barn / J. Chromatogr. A
- PMC3671520, PMC4963596 — Tβ4 wound healingNCBI PMC